HIV/AIDS treatment has improved significantly over the past few decades, transforming HIV infection from a fatal disease into a manageable chronic health condition. Although there is no complete cure for HIV, effective treatment is available worldwide in the form of Antiretroviral Therapy (ART). ART suppresses the replication of the Human Immunodeficiency Virus (HIV), allowing the immune system to recover and function effectively. This treatment has reduced AIDS-related deaths, increased life expectancy, and improved the quality of life of millions of people living with HIV. Antiretroviral Therapy (ART) is the standard treatment for HIV infection across the world. It involves the use of a combination of antiretroviral drugs that target different stages of the HIV life cycle. Using multiple drugs together reduces the chances of drug resistance and effectively lowers the amount of virus in the blood, known as the viral load. When the viral load becomes undetectable through regular treatment, the risk of transmitting HIV through sexual contact becomes extremely low, supporting the principle of "Undetectable = Untransmittable" (U=U). The major classes of antiretroviral drugs include Nucleoside Reverse Transcriptase Inhibitors (NRTIs), Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs), Protease Inhibitors (PIs), Integrase Strand Transfer Inhibitors (INSTIs), Entry Inhibitors, and Fusion