Question

Give a detailed account on the mechanism of phagocytosis.

29 Jan 2026
Answer :
Word Count : 254
Phagocytosis is a crucial cellular mechanism of the innate immune system that allows specialized cells, such as macrophages, neutrophils, and dendritic cells, to engulf and eliminate pathogens, debris, and apoptotic cells. The process begins with recognition and attachment, where phagocytic cells identify targets through pattern recognition receptors (PRRs) that bind to pathogen-associated molecular patterns (PAMPs) or opsonins like antibodies and complement proteins. Opsonization enhances phagocytosis by marking pathogens for more efficient recognition. Following attachment, the plasma membrane of the phagocyte undergoes actin-mediated rearrangement to
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