Question

Explain the role of toll like receptor in innate immunity.

29 Jan 2026
Answer :
Word Count : 237
Toll-like receptors (TLRs) are a critical component of the innate immune system, serving as pattern recognition receptors that detect conserved molecular structures present on pathogens, known as pathogen-associated molecular patterns (PAMPs). These receptors are expressed on various immune cells, including macrophages, dendritic cells, neutrophils, and epithelial cells, allowing the host to rapidly sense microbial invasion. Each TLR recognizes specific PAMPs; for example, TLR4 detects lipopolysaccharides from Gram-negative bacteria, TLR3 recognizes viral double-stranded RNA, and TLR9 binds
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