Question
Define DNA polymorphism? Examine any two techniques used in molecular genetics.
Answer :
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DNA polymorphism refers to the occurrence of two or more genetically distinct forms of DNA sequences within a population. The term polymorphism means “many forms” and, in human genetics, it describes variations in DNA sequence that are relatively common among individuals. Such variations may occur in coding or non-coding regions of the genome and can involve a single nucleotide, a short sequence, or differences in the number of repeated DNA segments. DNA polymorphisms are generally inherited and can serve as useful genetic markers for studying human variation, population structure, inheritance, disease susceptibility and relationships among individuals. One important type is the single nucleotide polymorphism (SNP), in which a single nucleotide differs between individuals. For example, one person may possess adenine at a particular position while another may possess guanine. Another type is variable number
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