IGNOU BBCCT 123 2026 - Describe transcription by RNA polymerase II, including core

Question

Describe transcription by RNA polymerase II, including core promoters and general transcription factors.

09 Feb 2026

Answer :

Word Count : 245

Transcription by RNA polymerase II in eukaryotes involves a series of steps that initiate gene expression. RNA polymerase II is responsible for synthesizing mRNA from a DNA template. The process begins at the core promoter, a specific DNA region located upstream of the gene. The core promoter typically contains elements such as the TATA box, which is found approximately 25-30 base pairs upstream of the transcription start site. This region is crucial for the binding of general transcription

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