Question
Describe the structure and function of prokaryotic RNA polymerase and the role of the sigma factor in transcription initiation.
Answer :
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Prokaryotic RNA polymerase is a multi-subunit enzyme responsible for transcribing DNA into RNA. It consists of a core enzyme and a sigma factor. The core enzyme is made up of five subunits: two alpha (α) subunits, one beta (β) subunit, one beta prime (β') subunit, and an omega (ω) subunit. These subunits together form the catalytic center of the enzyme, which is involved in RNA synthesis. The alpha subunits are involved in enzyme assembly and regulatory interactions, while the beta and beta prime subunits are responsible for the
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