Question
Ligases
Answer :
Word Count : 289
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Ligases are a class of enzymes that catalyze the joining of two separate molecules by forming a new covalent bond. This process is usually coupled with the hydrolysis of a high-energy phosphate bond from adenosine triphosphate (ATP) or a similar nucleoside triphosphate. Because of this energy requirement, ligases are also known as synthetases. They play an essential role in various biosynthetic processes, DNA repair, replication, and metabolic pathways. Ligases function by bringing two substrates into close proximity and facilitating the formation of bonds such as carbon–carbon (C–C),
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