Question

Give a brief account of lysosomal proteolysis.

29 Jan 2026
Answer :
Word Count : 231
Lysosomal proteolysis is a fundamental process in cellular metabolism and turnover, involving the degradation of proteins and other macromolecules within lysosomes. Lysosomes are membrane-bound organelles that contain a variety of hydrolytic enzymes, including proteases, nucleases, lipases, and glycosidases, which function optimally at acidic pH. Proteolysis within lysosomes primarily occurs through the action of proteases called cathepsins, which cleave peptide bonds in proteins to generate amino acids that can be reused by the cell for biosynthesis or energy production. Lysosomal proteolysis can be classified into two main pathways: endocytosis-mediated
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