Question
Explain Whole Genome Shotgun Sequencing Methods with diagram.
Answer :
Word Count : 277
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Whole Genome Shotgun Sequencing (WGS) is a method used to determine the complete DNA sequence of an organism’s genome by randomly breaking it into small fragments, sequencing them, and then assembling the sequences computationally. The process begins with the extraction of high-quality genomic DNA from the organism of interest. This DNA is then fragmented into numerous small pieces, usually ranging from 200 to 1000 base pairs. These fragments are inserted into vectors, commonly plasmids or bacterial artificial chromosomes,
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