Question
Explain the term 'isoenzymes'. Discuss the isoenzyme forms of Lactate Dehydrogenase (LDH) and their clinical significance.
Answer :
Word Count : 298
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Isoenzymes or isozymes are different molecular forms of the same enzyme that catalyze the same biochemical reaction but differ in their physical, chemical, kinetic, and immunological properties. They are usually produced by different genes or by different combinations of subunits. Isoenzymes are tissue specific and help in regulating metabolic activities according to the needs of different tissues. Their distribution pattern in body tissues makes them useful in clinical diagnosis because damage to a particular tissue releases characteristic isoenzymes into the
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