IGNOU BBCCT 105 2026 - Discuss how defects in protein folding lead to diseases such

Question

Discuss how defects in protein folding lead to diseases such as Alzheimer's disease and prion disorders.

09 Feb 2026

Answer :

Word Count : 239

Protein folding is a crucial process in maintaining cellular function, as it ensures that proteins acquire the correct three-dimensional structure necessary for their biological activity. When proteins fold improperly, it can lead to the formation of misfolded proteins, which are often non-functional or toxic to cells. In diseases like Alzheimer's and prion disorders, protein misfolding plays a central role in disease pathogenesis. In Alzheimer's disease, the accumulation of misfolded

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