Glutaraldehyde is a potent chemical disinfectant and sterilizing agent widely used in healthcare settings for high-level disinfection of medical equipment such as endoscopes, dialysis instruments, and surgical devices. Although it is effective in destroying microorganisms, its toxic nature poses significant health risks to humans when exposure occurs through inhalation, skin contact, or accidental ingestion. Healthcare workers, laboratory personnel, and sanitation staff are particularly vulnerable because of frequent occupational exposure. The adverse effects of glutaraldehyde depend on the concentration, duration, and route of exposure, and both acute and chronic health problems have been documented. One of the most common effects of glutaraldehyde exposure is irritation of the respiratory system. Vapors released during handling can cause symptoms such as coughing, throat irritation, chest tightness, wheezing, and shortness of breath. In sensitive individuals, prolonged exposure may lead to occupational asthma, which is characterized by airway inflammation and hyper-responsiveness. Workers exposed repeatedly may develop chronic respiratory conditions, making breathing difficult even at low concentrations. High concentrations can also cause severe inflammation of the lungs and mucous membranes, leading to long-term respiratory complications. Skin exposure is another significant concern. Glutaraldehyde is a strong irritant and sensitizing agent that can cause dermatitis upon contact. Symptoms may include redness, itching, burning sensation, dryness, and blistering of the