IGNOU BCHET 147 2026 - Which metal ion is essential for the process of blood coagulatio

Question

Which metal ion is essential for the process of blood coagulation? Explain the mechanism by which it facilitates clot formation? Give the different ways by which cadmium affects the human body.

10 Jan 2026

Answer :

Word Count : 249

Calcium ion (Ca²⁺) is essential for the process of blood coagulation. In bioinorganic chemistry, calcium acts as a cofactor for several clotting factors, including factors II (prothrombin), VII, IX, and X, by binding to γ-carboxyglutamate residues in these proteins. This binding facilitates the proper orientation of the clotting factors on phospholipid surfaces of platelets, enhancing the assembly of enzyme complexes

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