Prior Informed Consent (PIC) refers to a fundamental principle in the management of intellectual property rights, particularly in the context of biological resources, traditional knowledge, and genetic materials. It denotes the legal and ethical requirement that permission must be obtained from the rightful holders or custodians of resources or knowledge before accessing, using, or exploiting them for research, commercial, or industrial purposes. The concept of PIC ensures that the provider of the resource or knowledge is fully informed about the nature, scope, and potential consequences of its use, and that consent is given voluntarily without coercion or deception. The idea of Prior Informed Consent emerged prominently in international environmental and intellectual property frameworks to address concerns about biopiracy and the unauthorized use of indigenous knowledge and biological materials. It is closely associated with fairness, transparency, and equitable benefit-sharing. PIC serves as a protective mechanism for indigenous communities, local populations, and sovereign states by recognizing their rights over resources and knowledge that originate within their territories or traditions. The term “prior” implies that consent must be obtained before any access or utilization takes place. This ensures that the resource provider has an opportunity to assess the implications of granting access and can negotiate terms accordingly. “Informed” signifies that all relevant information must be disclosed to the provider, including the purpose of access, the methods of utilization, potential commercial applications, risks involved, and expected benefits. “Consent” indicates that the approval must be given freely and explicitly by the competent authority or community, reflecting their autonomous decision. In the management of intellectual property rights, PIC plays a crucial role in regulating access to genetic resources and traditional knowledge, which are often used in inventions, pharmaceuticals, agriculture, and biotechnology. It prevents the unauthorized patenting of inventions derived from such resources without acknowledging their origin or compensating the providers. By ensuring that PIC is obtained, legal systems aim to promote ethical research practices and prevent