Question
What are the limitations of Friedel-Crafts alkylation?
Answer :
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Limitations of Friedel-Crafts alkylations:
- The halide must be either an alkyl halide. Vinyl or aryl halides do not react (their intermediate carbocations are too unstable).
- Alkylation reactions are prone to carbocation rearrangements
- Deactivated benzenes are
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