Question
Explain the Strain and Distortion catalysis mechanism of enzyme.
Answer :
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Enzymes are biological catalysts that accelerate biochemical reactions by lowering the activation energy. Among the various mechanisms of enzyme catalysis, two important models are strain catalysis and distortion catalysis.
Strain catalysis occurs when the enzyme binds the substrate in such a way that it stresses certain bonds in the substrate, making them more susceptible to breaking. In this mechanism, the enzyme induces a conformational change in the substrate, distorting
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