Question
Explain DAG transacylase pathway for triglyceride synthesis.
Answer :
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The DAG transacylase pathway, also known as the Kennedy pathway, is a crucial biochemical route for triglyceride (TG) synthesis. It involves the esterification of diacylglycerol (DAG) with a fatty acyl-CoA molecule to form triglycerides. This pathway primarily takes place in the endoplasmic reticulum of liver, adipose tissue, intestine, and other lipid-metabolizing organs.
The process begins with the synthesis of phosphatidic acid (PA), which is formed by the sequential acylation
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