Question
Calculate the number of ATP produced by oxidation of one molecule of glucose by glycolysis and TCA cycle. Is this number less or more than that produced during β-oxidation of palmitic acid you attempted in question 6a?
Answer :
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The oxidation of one molecule of glucose through glycolysis, the tricarboxylic acid (TCA) cycle, and oxidative phosphorylation yields ATP as follows:
-
Glycolysis:
- 2 ATP are consumed in the preparatory phase.
- 4 ATP are produced in the energy-yielding phase.
- Net gain = 2 ATP
- 2 NADH are generated (yielding 5 ATP in the electron transport chain, assuming 2.5 ATP per NADH).
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Pyruvate to Acetyl-CoA Conversion:
- 2 molecules of pyruvate
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