Question
Explain Cori cycle and its significance.
Answer :
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The Cori cycle is a metabolic pathway that describes the recycling of lactate between skeletal muscle and the liver during conditions of anaerobic metabolism. When muscles are engaged in intense physical activity, the availability of oxygen becomes limited, and glucose is metabolized through glycolysis to pyruvate. In the absence of sufficient oxygen, pyruvate is reduced to lactate by the enzyme lactate dehydrogenase. This reaction allows the regeneration of NAD⁺, which is essential for the continuation of glycolysis and sustained ATP production in muscle cells. The lactate
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