Question
Explain cis-trans test of allelism (complementation test).
Answer :
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The cis-trans test of allelism, also known as the complementation test, is a genetic method used to determine whether two mutations producing a similar phenotype occur in the same gene or in different genes. The principle is based on the functional interaction of alleles within diploid organisms. If two mutations are crossed, the resulting heterozygote can reveal the relationship between them. When the heterozygote shows the mutant phenotype, it indicates that the mutations fail to complement each other, meaning both mutations lie in the same gene. This is referred to as the trans
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