IGNOU BBCET 141 2026 - Discuss the role of nutrients on excretion of drugs with suitable exam

Question

Discuss the role of nutrients on excretion of drugs with suitable examples.

03 Feb 2026

Answer :

Word Count : 278

Nutrients play an important role in the excretion of drugs by influencing absorption, metabolism, renal function, and biliary elimination. Diet composition can modify the rate at which drugs are eliminated from the body, thereby affecting their therapeutic efficacy and toxicity. Proteins are especially significant because they regulate hepatic enzyme activity. A high-protein diet enhances liver microsomal enzymes, increasing the metabolism and excretion of drugs such as phenytoin and theophylline. In contrast, protein deficiency reduces enzyme activity, leading to delayed drug clearance and possible accumulation. Carbohydrates also affect drug excretion by altering urinary pH and renal blood flow. Diets rich in carbohydrates may reduce

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