IGNOU BBCCT 123 2026 - Describe the structure and function of prokaryotic RNA polymerase and

Question

Describe the structure and function of prokaryotic RNA polymerase and the role of the sigma factor in transcription initiation

10 Feb 2026

Answer :

Word Count : 259

Prokaryotic RNA polymerase is a multi-subunit enzyme responsible for transcription of DNA into RNA and plays a central role in gene expression and regulation. The core enzyme consists of five subunits: two alpha (α) subunits, one beta (β), one beta prime (β′), and one omega (ω) subunit, forming the structure α2ββ′ω. The α subunits are involved in enzyme assembly and interaction with regulatory proteins. The β subunit

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