IGNOU BBCCT 105 2026 - Describe the principles of X-ray diffraction and NMR spectroscopy used

Question

Describe the principles of X-ray diffraction and NMR spectroscopy used in protein structure determination.

09 Feb 2026

Answer :

Word Count : 258

X-ray diffraction and Nuclear Magnetic Resonance (NMR) spectroscopy are two powerful techniques used in protein structure determination, each offering unique insights into molecular details. X-ray diffraction relies on the principle that when a protein crystal is exposed to X-ray radiation, the X-rays are diffracted by the crystal lattice. By measuring the angles and intensities of these diffracted rays, a diffraction pattern is generated. This pattern

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