Question
Describe the phenomenon of substrate channeling observed in the conversion of pyruvate
into acetyl Co-A.
Answer :
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Substrate channeling is a phenomenon observed in biochemical pathways where intermediates of a reaction are passed directly from one enzyme to another without being released into the bulk solvent. In the context of pyruvate conversion into acetyl Co-A, substrate channeling plays a crucial role in maintaining the efficiency of this metabolic process.
In glycolysis, pyruvate is produced from glucose and serves as a central
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