Question
Concerted (MWC) model and Sequential (KNF) model of allosteric enzyme
Answer :
Word Count : 121
| Feature | Concerted (MWC) Model | Sequential (KNF) Model |
|---|---|---|
| Full form | Monod-Wyman-Changeux model | Koshland-Némethy-Filmer model |
| Conformational change | All subunits switch simultaneously from T ↔ R | Subunits change one by one upon substrate binding |
| Subunit interaction | Highly cooperative; all subunits act together | Cooperativity is gradual, depends on sequential binding |
| Binding effect | Ligand binding shifts equilibrium toward R state | Ligand binding induces conformational ____ _____ _____ _________ ______ ______ ____ ______ ______ ____. ________ ___ ___ ____ ______ _________ _______ ________ _____ ________ ___. _______ _________ ___ _____ _____ ________ _______ _________ ______ ____ __________ _________. ______ _______ ____ ________ ____ ______ ________ ___. ______ ___ _______ _____ _________ ____ ___ ___ _______ ________ _______ _____. ___ ________ ___ ________ ____ _______ ______ _____. _______ _______ ________ ____ _________ ___ _____ __________. _______ _________ ___ ________ ________ ______ _______. IGNOU ACADEMY Your IGNOU journey, made easier.
Continue Reading — It's Free Sign in with Google to unlock more of this answer. ✓ Free access ✓ Unlock up to 60% of the answer ✓ No payment required Quick Google sign-in. No separate registration form. |