Question
CD8 Cytotoxic T-cells
Answer :
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CD8 cytotoxic T-cells, also known as cytotoxic T lymphocytes (CTLs), are specialized immune cells that play a crucial role in cell-mediated immunity by directly killing infected, abnormal, or cancerous cells. They develop in the bone marrow and mature in the thymus, where they acquire CD8 surface glycoproteins and T-cell receptors (TCRs). These receptors enable them to recognize specific antigens presented on Major Histocompatibility Complex class I (MHC-I) molecules, which are expressed on nearly all nucleated cells. Activation of CD8 T-cells requires antigen recognition along with co-stimulatory signals provided by antigen-presenting cells such as dendritic cells. Helper T-cells (CD4⁺)
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