Describe the relationship between infection and malnutrition. Briefly discuss the effect of Malnutrition on the growth and development of a child.
The strong relationship between malnutrition and infection was originally described by Scrimshaw et al. From this framework, much investigation was done in this area and there is a total agreement among authors that mortality is significantly more elevated in undernourished child compared to healthy ones. The study by Man et al. , which included a large population of hospitalized Gambian children, clearly illustrated the relationship between undernourishment, characterized by lower weight relative to age, and higher mortality indexes associated with many infectious diseases.
One-third of the world's population is infected with M. tuberculosis, the main agent that provokes death among infectious diseases. This infection is particularly influenced by undernutrition and is a major cause of morbidity and mortality in developing countries where PCM is also prevalent . Furthermore, malnutrition as an important risk for tuberculosis has also being reinforced by findings in experimental models . Similarly, undernutrition may also affect the clinical outcome of tuberculosis . A recent meta-analysis suggested
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