Question
Discuss how inhibitors of bacterial transcription act as antimicrobial agents and explain their mode of action.
Answer :
Word Count : 249
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Inhibitors of bacterial transcription act as effective antimicrobial agents by targeting the essential process of RNA synthesis in bacteria. Transcription is carried out by DNA-dependent RNA polymerase, which synthesizes RNA from a DNA template. Since gene expression is necessary for bacterial growth, metabolism, and replication, blocking transcription prevents the production of vital proteins and ultimately
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