Question
Differentiated features of SIADH & CSW
Answer :
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Syndrome of Inappropriate Antidiuretic Hormone secretion (SIADH) and Cerebral Salt Wasting (CSW) are both conditions characterized by hyponatremia, but they have distinct pathophysiological mechanisms, clinical features, and treatment approaches. In SIADH, there is excessive secretion of antidiuretic hormone (ADH), leading to water retention by the kidneys, which dilutes the serum sodium levels. This condition is commonly seen in malignancies, CNS disorders, and pulmonary diseases. The hallmark of SIADH is a low serum sodium concentration with normal or high urine sodium levels and urine osmolality greater than plasma osmolality, indicating
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