Question
Differentiate between Mass spectrometry and Nuclear Magnetic Resonance (NMR).
Answer :
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Mass spectrometry and Nuclear Magnetic Resonance represent two fundamental analytical platforms in OMICS, yet they differ significantly in principles, data output, and applications. Mass spectrometry operates by ionizing molecules and measuring their mass-to-charge ratios to generate spectra that reveal molecular mass, fragmentation patterns, and relative abundance. It is highly sensitive, enabling detection of low-abundance metabolites, peptides, and proteins in complex biological samples, which makes
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