IGNOU BBCCT 123 2026 - Describe transcription by RNA polymerase II, including core

Question

Describe transcription by RNA polymerase II, including core promoters and general transcription factors.

10 Feb 2026

Answer :

Word Count : 252

Transcription by RNA polymerase II is a central process in eukaryotic gene expression, responsible for synthesizing messenger RNA (mRNA) from DNA. This process begins at the core promoter, a DNA sequence located immediately upstream of the transcription start site. Core promoters contain specific motifs such as the TATA box, Initiator (Inr), and downstream promoter elements (DPE), which serve as binding sites for the transcription machinery. The presence and

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