Question
आरएनए हस्तक्षेप की क्रियाविधि की व्याख्या कीजिए और जीन साइलेंसिंग और चिकित्सा में इसके अनुप्रयोगों पर चर्चा कीजिए।
Answer :
Word Count : 254
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आरएनए हस्तक्षेप (RNA interference, RNAi) एक जैविक प्रक्रिया है जिसके द्वारा कोशिका विशिष्ट जीन की अभिव्यक्ति को नियंत्रित या अवरुद्ध करती है। यह प्रक्रिया मुख्यतः डबल-स्ट्रैंडेड आरएनए (dsRNA) अणुओं के माध्यम से संचालित होती है। जब कोशिका में dsRNA प्रवेश करता है, तब डाइसर (Dicer) नामक एंजाइम इसे छोटे-छोटे खंडों में काट देता है, जिन्हें स्मॉल इंटरफेरिंग आरएनए
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