Question
समझाइए कि वैकल्पिक स्प्लिसिंग और आरएनए संपादन यूकैरियोट्स में प्रोटिओमिक विविधता में कैसे योगदान करते हैं।
Answer :
Word Count : 239
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RNA interference (RNAi) is a cellular mechanism that regulates gene expression post-transcriptionally by degrading specific messenger RNA (mRNA) molecules or inhibiting their translation. The process begins when double-stranded RNA (dsRNA) enters the cell, either endogenously or through experimental introduction. The enzyme Dicer recognizes and cleaves dsRNA into small interfering RNAs (siRNAs) of about 21–23 nucleotides. These siRNAs are then incorporated into the RNA-induced silencing complex (RISC), where the passenger strand is removed, leaving the guide strand to pair with complementary sequences on target mRNA. Once binding occurs, RISC mediates cleavage of
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