IGNOU BSCBCH BBCCT 123 Gene Expression and Regulation Solved Assignment ENGLISH
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BBCCT 123: Gene Expression and Regulation
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| Title Name | IGNOU BSCBCH BBCCT 123 Gene Expression and Regulation Solved Assignment ENGLISH |
|---|---|
| Type | Soft Copy (E-Assignment) .pdf |
| University | IGNOU |
| Degree | BACHELOR DEGREE PROGRAMMES |
| Course Code | BSCBCH |
| Course Name | B.Sc. Honours in Biochemistry |
| Subject Code | BBCCT 123 |
| Subject Name | Gene Expression and Regulation |
| Year | 2026 |
| Session | - |
| Language | ENGLISH |
| Assignment Code | BBCCT 123/Assignment-1/2026 |
| Product Description | Assignment of BSCBCH (B.Sc. Honours in Biochemistry) 2026. Latest BBCCT 123 2026 Solved Assignment Solutions |
| Format | Ready-to-Print PDF (.soft copy) |
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BBCCT 123 (January 2026 - July 2026) - ENGLISH
ASSIGNMENT
GENE EXPRESSION AND REGULATION
Course Code: BBCCT-123
Assignment Code: BBCCT-123/TMA/2026
Maximum Marks: 100
Answer all the questions given below. All Questions carry equal marks.
1.
A) Describe the structure and function of prokaryotic RNA polymerase and the role of the sigma factor in transcription initiation.
B) Explain how DNA foot printing is used to identify promoter regions.
2.
A) Describe the three stages of transcription in prokaryotes, highlighting rho-dependent and rho-independent termination.
B) Discuss how inhibitors of bacterial transcription act as antimicrobial agents and explain their mode of action.
3.
A) Describe transcription by RNA polymerase II, including core promoters and general transcription factors.
B) Explain how differences between prokaryotic and eukaryotic transcription influence gene regulation complexity in eukaryotes.
4.
A) Describe the roles of RNA polymerases I and III in eukaryotic transcription.
B) Compare the fidelity of transcription and DNA replication and discuss the biological significance of transcriptional errors.
5.
A) Describe the mechanism of pre-mRNA splicing and the role of the spliceosome.
B) Explain how alternative splicing and RNA editing contribute to proteomic diversity in eukaryotes.
6.
A) Explain the salient features genetic code.
B) Discuss how wobble base pairing allows efficient translation with a limited number of tRNAs.
7.
A) Describe the structure and functions of mRNA and tRNA in protein synthesis.
B) Explain how antibiotics have been used to elucidate the mechanism of translation and their clinical applications.
8.
A) Describe the role of signal sequences in protein targeting to different cellular compartments.
B) Explain the physiological significance of regulated protein degradation in cell cycle control and stress responses.
9.
A) Explain the principles of positive and negative regulation of gene expression with reference to operons.
B) Explain how coordinated regulation of ribosomal protein synthesis is achieved in prokaryotes.
10.
A) Differentiate between euchromatin and heterochromatin and explain chromatin remodeling.
B) Explain the mechanism of RNA interference and discuss its applications in gene silencing and therapeutics.
BBCCT 123 (January 2026 - July 2026) - HINDI
सत्रीय कार्य पुस्तिका
जीन अभिव्यक्ति और नियमन
Course Code: BBCCT-123
Assignment Code: BBCCT-123/TMA/2026
Maximum Marks: 100
नीचे दिये गये सभी प्रश्नों के उत्तर दीजिये। सभी प्रश्नों के अंक समान है।
1. अ) प्रोकैरियोटिक आरएनए पॉलीमरेज की संरचना और कार्य तथा प्रतिलेखन आरंभ में सिग्मा कारक की भूमिका का वर्णन कीजिए। 5
ब) बताइए कि प्रमोटर क्षेत्रों की पहचान करने के लिए डीएनए फुट प्रिंटिंग का उपयोग कैसे किया जाता है। 5
2. अ) प्रोकैरियोट्स में प्रतिलेखन के तीन चरणों का वर्णन कीजिए, जिसमें रो-निर्भर और रो-स्वतंत्र समापन पर विशेष ध्यान दीजिए। 5
ब) बैक्टीरिया के प्रतिलेखन के अवरोधक रोगाणुरोधी एजेंटों के रूप में कैसे कार्य करते हैं, इस पर चर्चा कीजिए और उनकी कार्यप्रणाली समझाइए। 5
3. अ) कोर प्रमोटर और सामान्य प्रतिलेखन कारकों सहित आरएनए पॉलीमरेज II द्वारा प्रतिलेखन का वर्णन कीजिए। 5
ब) प्रोकैरियोटिक और यूकैरियोटिक प्रतिलेखन के बीच अंतर यूकैरियोट्स में जीन विनियमन की जटिलता को कैसे प्रभावित करते हैं, यह समझाइए। 5
4. अ) यूकैरियोटिक प्रतिलेखन में आरएनए पॉलीमरेज I और III की भूमिकाओं का वर्णन कीजिए। 5
ब) प्रतिलेखन और डीएनए प्रतिकृति की सटीकता की तुलना कीजिए और प्रतिलेखन त्रुटियों के जैविक महत्व पर चर्चा कीजिए। 5
5. अ) प्री-एमआरएनए स्प्लिसिंग की क्रियाविधि और स्प्लिसियोसोम की भूमिका का वर्णन कीजिए। 5
ब) समझाइए कि वैकल्पिक स्प्लिसिंग और आरएनए संपादन यूकैरियोट्स में प्रोटिओमिक विविधता में कैसे योगदान करते हैं। 5
6. अ) आनुवंशिक कोड की प्रमुख विशेषताओं की व्याख्या कीजिए। 5
ब) चर्चा कीजिए कि वोबल बेस पेयरिंग सीमित संख्या में टीआरएनए के साथ कुशल अनुवाद को कैसे संभव बनाती है। 5
7. अ) प्रोटीन संश्लेषण में tRNA और mRNA की संरचना और कार्यों का वर्णन कीजिए। 5
ब) अनुवाद की क्रियाविधि को स्पष्ट करने में एंटीबायोटिक दवाओं के उपयोग और उनके नैदानिक अनुप्रयोगों की व्याख्या कीजिए। 5
8. अ) विभिन्न कोशिकीय भागों में प्रोटीन के लक्ष्यीकरण में संकेत अनुक्रमों की भूमिका का वर्णन कीजिए। 5
ब) कोशिका चक्र नियंत्रण और तनाव प्रतिक्रियाओं में विनियमित प्रोटीन अपघटन के शारीरिक महत्व की व्याख्या कीजिए। 5
9. अ) ऑपेरॉन के संदर्भ में जीन अभिव्यक्ति के सकारात्मक और नकारात्मक विनियमन के सिद्धांतों की व्याख्या कीजिए। 5
ब) प्रोकैरियोट्स में राइबोसोमल प्रोटीन संश्लेषण का समन्वित विनियमन कैसे प्राप्त किया जाता है, इसकी व्याख्या कीजिए। 5
10. अ) यूक्रोमैटिन और हेटरोक्रोमैटिन में अंतर स्पष्ट कीजिए और क्रोमेटिन रीमॉडलिंग की व्याख्या कीजिए। 5
ब) आरएनए हस्तक्षेप की क्रियाविधि की व्याख्या कीजिए और जीन साइलेंसिंग और चिकित्सा में इसके अनुप्रयोगों पर चर्चा कीजिए। 5
BBCCT 123 2025 - English
ASSIGNMENT
GENE EXPRESSION AND REGULATION
Course Code: BBCCT-123
Assignment Code: BBCCT-123/TMA/2025
Maximum Marks: 100
Answer all the questions given below.
1. A) Define transcription and explain its significance in molecular biology.
B) Differentiate between transcription and DNA replication in terms of enzymes and processes involved.
2. A) What are the primary differences between prokaryotic and eukaryotic transcription?
B) Explain the role and structure of RNA polymerase in prokaryotic transcription.
3. What is a promoter, and how does it contribute to the initiation of transcription?
4. A) Illustrate the DNA footprinting technique and discuss its importance.
B) Describe the processes involved in the maturation of eukaryotic mRNA, including the addition of the cap and Poly-A tail.
5. A) What are exons and introns, and how are they related to RNA splicing?
B) Explain the concept of the genetic code and its role in translation.
6. A) Describe the steps of translation, including initiation, elongation, and termination.
7. Discuss the operon concept and its significance in prokaryotic gene regulation.
8. Explain chromatin remodeling and its role in gene expression in eukaryotes.
9. A) How do environmental conditions influence gene expression in prokaryotes? Provide examples.
10. How are antibiotics used to inhibit transcription in prokaryotes? Provide examples of such inhibitors.
BBCCT 123 2025 - Hindi
सत्रीय कार्य
जीन अभिव्यक्ति और नियमन
पाठ्यक्रम कोड: BBCCT-123
सत्रीय कार्य कोड: BBCCT-123/TMA/2025
कुल अंक : 100
नीचे दिये गये सभी प्रश्नों के उत्तर दीजिये। सभी प्रश्नों के अंक समान है।
1. ए) प्रतिलेखन को परिभाषित करें और आणविक जीव विज्ञान में इसके महत्व की व्याख्या करें।
बी) एंजाइमों और प्रक्रियाओं के संदर्भ में प्रतिलेखन और डीएनए प्रतिकृति के बीच अंतर करें।
2. ए) प्रोकैरियोटिक और यूकेरियोटिक प्रतिलेखन के बीच प्राथमिक अंतर क्या हैं?
बी) प्रोकैरियोटिक प्रतिलेखन में आरएनए पोलीमरेज की भूमिका और संरचना की व्याख्या करें।
3. प्रमोटर क्या है, और यह प्रतिलेखन की शुरुआत में कैसे योगदान देता है?
4. ए) डीएनए फुटप्रिंटिंग तकनीक का वर्णन करें और इसके महत्व पर चर्चा करें।
बी) कैप और पॉली-ए टेल को जोड़ने सहित यूकेरियोटिक एमआरएनए की परिपक्वता में शामिल प्रक्रियाओं का वर्णन करें।
5. ए) एक्सॉन और इंट्रॉन क्या हैं, और वे आरएनए स्प्लिसिंग से कैसे संबंधित हैं?
बी) आनुवंशिक कोड की अवधारणा और अनुवाद में इसकी भूमिका की व्याख्या करें।
6. अनुवाद के चरणों का वर्णन करें, जिसमें आरंभ, विस्तार और समाप्ति शामिल हैं।
7. ऑपेरॉन अवधारणा और प्रोकैरियोटिक जीन विनियमन में इसके महत्व पर चर्चा करें।
8. यूकेरियोट्स में क्रोमेटिन रीमॉडलिंग और जीन अभिव्यक्ति में इसकी भूमिका की व्याख्या करें।
9. पर्यावरणीय परिस्थितियाँ प्रोकैरियोट्स में जीन अभिव्यक्ति को कैसे प्रभावित करती हैं? उपलब्ध करवाना उदाहरण ।
10. प्रोकैरियोट्स में प्रतिलेखन को बाधित करने के लिए एंटीबायोटिक दवाओं का उपयोग कैसे किया जाता है? ऐसे अवरोधकों के उदाहरण प्रदान करें।
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Course: B.Sc. Honours in Biochemistry (BSCBCH)
Subject: BBCCT 123 - Gene Expression and Regulation
Session: January 2026 - December 2026
Language: ENGLISH
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Product Information
| Course Name | B.Sc. Honours in Biochemistry |
| Course Code | BSCBCH |
| Subject Code | BBCCT 123 |
| Subject | Gene Expression and Regulation |
| Programme | BACHELOR DEGREE PROGRAMMES Courses |
| Language | ENGLISH |
| Material Type | Solved Assignment – Soft Copy / PDF |
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