Question

With the help of diagrams explain the steps of nuclear transplantation experiment in frog eggs.

28 Jan 2026
Answer :
Word Count : 279
Nuclear transplantation is a classical experiment in developmental biology used to study nuclear totipotency and cloning. It involves transferring a nucleus from a donor cell into an enucleated recipient egg cell. The experiment in frog eggs, particularly using *Xenopus laevis*, consists of several key steps. First, the recipient frog egg is collected and enucleated. Enucleation means the removal of the egg’s nucleus, which is done using a fine glass needle under a microscope. This creates an egg cell devoid of its genetic material but still containing all the cytoplasmic components necessary for development. Next, a donor nucleus is isolated from a somatic cell
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