Question
Which factors make kidney susceptible to nephrotoxicity? How does cyclosporin cause injury to kidneys?
Answer :
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The kidney is particularly susceptible to nephrotoxicity due to its unique anatomy and physiology. The high blood flow through the kidneys, approximately 25% of the cardiac output, increases the exposure of renal tissues to toxic substances. Furthermore, the kidneys are involved in the filtration and excretion of waste products, meaning they are constantly in contact
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