What are the factor affecting the potency of drug during storage?
The potency of a drug during storage can be influenced by several factors. Ensuring that drugs remain effective and safe over their shelf life is a critical concern in drug regulatory affairs. Some of the key factors affecting the potency of drugs during storage include:
1. Temperature: Temperature plays a crucial role in drug stability. Most drugs have specific storage temperature requirements, and deviation from these can lead to chemical degradation, alteration in drug structure, and loss of potency. Extremes of temperature, both too high and too low, can be detrimental.
2. Humidity: Moisture in the air can cause physical and chemical changes in drugs. It can lead to degradation, spoilage, or changes in the solubility of the active
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