IGNOU LSE 5 2026 - Role of calcium in regulation of muscle contraction

Question

Role of calcium in regulation of muscle contraction

28 Jan 2026

Answer :

Word Count : 252

Calcium ions (Ca²⁺) play a central role in the regulation of muscle contraction in both skeletal and cardiac muscles. Muscle contraction is initiated when an action potential travels along the sarcolemma and into the transverse (T) tubules, triggering the release of Ca²⁺ from the sarcoplasmic reticulum (SR) into the cytosol. The increase in cytosolic Ca²⁺ concentration is the key signal that links electrical excitation to mechanical contraction, a process known as excitation–contraction coupling. In skeletal muscle, Ca²⁺ binds

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