Question
In what way is NMR spectrometry different from other molecular spectroscopic methods?
Answer :
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Nuclear Magnetic Resonance spectrometry differs fundamentally from other molecular spectroscopic methods in the nature of the interaction involved, the type of transitions observed, and the kind of structural information obtained. While most molecular spectroscopic techniques such as UV–Visible, infrared, Raman, and microwave spectroscopy involve interactions of electromagnetic radiation with electrons or molecular vibrations and rotations, NMR spectrometry is based on the interaction of radiofrequency radiation with the magnetic moments of atomic nuclei placed in a strong external magnetic field. In NMR spectrometry, the transitions occur between nuclear spin energy levels that arise due to the alignment of nuclear magnetic moments with or against an applied magnetic field. Only nuclei possessing a non-zero nuclear spin, such as ¹H, ¹³C, ¹⁹F, and ³¹P, are NMR-active. In contrast, other spectroscopic methods do not depend on nuclear spin properties but on electronic, vibrational, or rotational energy levels that are common to all molecules. As
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