IGNOU BZYCT 137 2026 - Explain the clinical significance of Rh antigens in human blood.

Question

Explain the clinical significance of Rh antigens in human blood.

31 Jan 2026

Answer :

Word Count : 455

The Rh antigens, particularly the D antigen, are surface proteins present on red blood cells and play a crucial role in transfusion medicine and prenatal care. The presence or absence of these antigens determines an individual's Rh blood group as either Rh-positive or Rh-negative. Clinically, Rh antigens are significant because they can trigger immune responses when an Rh-negative individual is exposed to Rh-positive blood, leading to the production of anti-D antibodies. This immune response is central to several medical conditions, including hemolytic transfusion reactions and hemolytic disease of the fetus and

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