Question

Explain the base excision repair mechanism with the help of a suitable diagram.

06 Feb 2026
Answer :
Word Count : 216
Base excision repair (BER) is a crucial DNA repair mechanism that corrects small, non-helix-distorting base lesions caused by oxidative damage, alkylation, or deamination. The process starts with the recognition of a damaged base by a DNA glycosylase enzyme. This enzyme identifies and removes the damaged base, creating an abasic site (AP site). After the base is excised, the
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