Actin filaments are dynamic components of the cytoskeleton that play crucial roles in cell shape, motility, intracellular transport, and division. Several drugs can specifically target actin filaments, either stabilizing or destabilizing them, thereby affecting cellular processes. Phalloidin, a toxin derived from the Amanita phalloides mushroom, binds tightly to filamentous actin (F-actin) and prevents its depolymerization. This stabilizing effect inhibits normal actin turnover, resulting in rigid filaments that disrupt processes like endocytosis and cell motility. Cytochalasins, produced by fungi, bind to the barbed (+)