“Drug nutrient interaction” is an important consideration in the nutritional management of Parkinson’s disease, Justify the statement giving appropriate examples.
Many theories of the cause of PD symptoms point to the death of dopamine producing neurons within the central nervous system due to oxidative stress. This oxidative stress is caused by metabolism and the production of molecules known as free radicals. Upon accumulation of these free radicals within the brain, they can cause damage to neurons. Additionally, dopamine producing neurons are particularly vulnerable to oxidative stress due to the relatively high levels of metabolism associated with the production of dopamine, resulting in comparatively higher amounts of free radicals being produced by these dopamine producing neurons. The effects of dopamine within the brain are widespread, including the control of voluntary motor control. With the death of these dopamine producing cells within an area of the mid brain known as the substantia nigra, the central nervous system has less control over the body, resulting in the tremors
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