IGNOU LSE 6 2018 - Outline the stages of carcinogenesis.

Question

Outline the stages of carcinogenesis.

23 Jan 2018

Answer :

Word Count : 442

Cancer biologists have realised now that the i processes of carcinogenesis is very complex, involving many events but to simplify the process it can be divided into at least three stages initiation, promotion and progression.

1) Initiation - The fist stage initiation results from an irreversible genetic alteration, most likely one or more mutations. It is difficult to identify and isolate initiated cells, except in some experimental conditions. One such example is the initiation of liver cancer in
rats by a known chemical carcinogen aflatoxin. Most initiated

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