Question
Compare the prokaryotic DNA replication and eukaryotic DNA replication.
Answer :
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DNA replication in prokaryotes and eukaryotes follows the semi-conservative principle but differs significantly in complexity, organization, and regulation. Prokaryotic DNA replication occurs in organisms such as bacteria, which typically possess a single, circular chromosome. Replication begins at a single origin of replication called oriC and proceeds bidirectionally. The process is rapid and efficient, coordinated with the cell cycle, and usually completed before cell division. DNA polymerase III is the main enzyme responsible for chain elongation, while DNA polymerase I removes RNA primers and fills gaps. Replication occurs in the cytoplasm, as prokaryotes lack a defined nucleus. In contrast, eukaryotic DNA replication
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