Question
What do you understand by SAR? How is it important?
Answer :
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Structure–Activity Relationship (SAR) is a scientific approach used in drug regulatory affairs to understand the relationship between the chemical structure of a compound and its biological activity. It focuses on identifying how changes in the molecular structure of a drug candidate affect its pharmacological effects, potency, selectivity, and toxicity. SAR studies involve systematic modifications of functional groups, substituents, or stereochemistry in
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