Metabolic diseases are disorders that disrupt the normal biochemical processes through which the body converts food into energy, builds tissues, and eliminates waste products. These disorders occur due to defects in enzymes, hormones, or metabolic pathways, leading to either the accumulation of toxic substances or the deficiency of essential compounds. Metabolic diseases may be inherited, caused by genetic mutations, or acquired due to environmental factors, poor nutrition, hormonal imbalance, or lifestyle. Medical anthropology examines these diseases not only from a biological perspective but also in relation to culture, environment, dietary practices, and access to healthcare. One of the most common metabolic diseases is Diabetes Mellitus, characterized by elevated blood glucose levels resulting from insufficient insulin production or resistance to insulin. Type 1 diabetes is an autoimmune disorder where the pancreas fails to produce insulin, while Type 2 diabetes is associated with obesity, sedentary lifestyles, and genetic predisposition. Symptoms include excessive thirst, frequent urination, fatigue, weight loss, and blurred vision. If untreated, diabetes can lead to cardiovascular diseases, kidney failure, nerve damage, and vision impairment. Lifestyle modification, medication, and insulin therapy