IGNOU BBCCT 101 2026 - Explain how alterations in protein secondary or tertiary str

Question

Explain how alterations in protein secondary or tertiary structure can lead to loss of biological activity.

10 Feb 2026

Answer :

Word Count : 264

Proteins acquire their biological activity from their specific three-dimensional structure, which is determined by the folding of the polypeptide chain into secondary and tertiary levels of organization. The secondary structure refers to local folding patterns such as alpha helices and beta pleated sheets, stabilized mainly by hydrogen bonds between the backbone atoms. The tertiary structure represents the overall three-dimensional conformation formed

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