Question
Discuss the major opportunistic infections and gynaecological complications associated with HIV-positive women.
Answer :
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HIV-positive women are particularly vulnerable to a range of opportunistic infections and gynecological complications due to the immunosuppressive nature of the virus. The progression of HIV weakens the immune system, making it harder for the body to fight off infections that would otherwise be controlled in healthy individuals. As a result, these infections are one of the leading causes of morbidity and mortality among HIV-positive women. One of the most common opportunistic infections in HIV-positive women is candidiasis, or fungal infections caused by *Candida* species. These infections often affect the vaginal and oral mucosa, leading to conditions like vaginal yeast infections or thrush. Women with HIV experience these infections more frequently and with greater severity due to the compromised immune function. Symptoms of vaginal candidiasis include itching, abnormal discharge, and irritation. Treatment usually involves antifungal medications, but recurrent infections can be a significant issue for these women. Another common opportunistic infection is tuberculosis (TB), which remains a leading cause of death among individuals with HIV. TB primarily affects the lungs but can also affect other parts of the body, including the reproductive organs. HIV-positive women are more susceptible to developing active TB, especially in areas with high HIV prevalence, such as Sub-Saharan Africa. Symptoms of TB include persistent cough, weight loss, and night sweats. The interaction between HIV and TB complicates the treatment process, as TB treatment can be more challenging for individuals with HIV due to drug interactions and the weakened state of the immune system. Sexually transmitted infections (STIs) are also more prevalent among HIV-positive women, with conditions like herpes simplex virus (HSV) and
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