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Immune Mechanisms
Antibody and secondary biologic activities
For some pathogens such as meningococci (Gram-negative), the antigen-antibody configuration will activate the serum complement protein cascade resulting in lysis or phagocytosis of many bacteria. Gram-positive organisms are killed by antibody-initiated complement-dependent opsonophagocytosis and intracellular killing. The exact protective mechanism of viral-specific antibodies is not fully known and may be unique for each pathogen. Antibodies that
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